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2 741 808

(13)

(51)

IPC

C07D471/04(2006-01-01)

C07D487/04(2006-01-01)

A61K31/407(2006-01-01)

A61K31/437(2006-01-01)

A61K31/444(2006-01-01)

A61P35/00(2006-01-01)

A61P31/18(2006-01-01)

A61P13/12(2006-01-01)

A61P3/10(2006-01-01)

(21) (22)

Application

2018140061, 2017-04-14

(24)

Start date

2017-04-14

(22)

Actual filing date

2017-04-14

(45)

Published

2021-01-28

(72)

Inventor

Fidanze, Steven D.Hasvold, Lisa A.Liu, DachunMcdaniel, Keith F.Pratt, JohnSchrimpf, MichaelSheppard, George S.Wang, LeLi, Bing

(73)

Holder

Abbvie Inc.

BROMODOMAIN INHIBITORS Russian patent published in 2021 - IPC C07D471/04 C07D487/04 A61K31/407 A61K31/437 A61K31/444 A61P35/00 A61P31/18 A61P13/12 A61P3/10

Abstract RU 2741808 C2

FIELD: organic chemistry.

SUBSTANCE: invention relates to N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl]-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide or its pharmaceutically acceptable salt.

EFFECT: obtaining a novel heterocyclic compound which is a bromodomain (BET) inhibitor which is selective with respect to binding domain II (BDII).

2 cl, 2 tbl, 129 ex

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RU 2 741 808 C2

Authors

Fidanze, Steven D.

Hasvold, Lisa A.

Liu, Dachun

Mcdaniel, Keith F.

Pratt, John

Schrimpf, Michael

Sheppard, George S.

Wang, Le

Li, Bing

Dates

2021-01-28—Published

2017-04-14—Filed