FIELD: biochemistry.
SUBSTANCE: invention relates to a new biologically active compound—a peptide with antidepressant activity, and can be used to create a drug for treating the depressive state of patients by using a tetrapeptide which is acetyl-D-LYS-LYS-ARG-ARG-amide for the given purposes.
EFFECT: expressed antidepressant properties of the preparation, manifested both in intact animals, and in animals with the model of reserpine-induced depression.
1 cl, 7 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PEPTIDE FOR TREATMENT OF ALZHEIMER'S DISEASE | 2017 |
|
RU2678987C2 |
| ANTIDEPRESSANT FOR CORRECTION OF SIDE EFFECTS FROM NEUROLEPTICS | 2019 |
|
RU2746012C2 |
| 9-[2-(4-ISOPROPYLPHENOXY)ETHYL]ADENINE POSSESSING ANTIDEPRESSANT AND STRESS-RELIEVING ACTION | 2013 |
|
RU2529817C1 |
| PHARMACEUTICALLY ACCEPTABLE ACETYL-(D-LYS)-LYS-ARG-ARG-AMIDE PEPTIDE SALTS | 2021 |
|
RU2763136C1 |
| TETRAPEPTIDE AND PREPARATION, POSSESSING CEREBROPROTECTIVE AND ANTIAMNESTIC ACTIVITIES (VERSIONS) | 2013 |
|
RU2537560C2 |
| SUBSTANCE ELICITING ANTIDEPRESSANT ACTIVITY | 2003 |
|
RU2232578C1 |
| ANTIDEPRESSANT, ANXIOLYTIC, NEUROPROTECTIVE AND IMMUNOSTIMULATING AGENT | 2010 |
|
RU2429834C1 |
| PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF DEPRESSIONS | 2011 |
|
RU2475235C2 |
| 2-BROMO-1-(THIETANYL-3)IMIDAZOLE-4,5-DICARBOXYLIC ACID DERIVATIVES EXHIBITING ANTIDEPRESSANT ACTIVITY | 2014 |
|
RU2537948C1 |
| ANTIDEPRESSANT | 2012 |
|
RU2535027C2 |
