PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF DEPRESSIONS Russian patent published in 2013 - IPC A61K31/135 A61K31/343 A61K31/4045 A61K31/4525 A61K47/00 A61K9/02 A61K9/20 A61K9/28 A61K9/48 A61P25/20 A61P25/24 

Abstract RU 2475235 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a pharmaceutical composition for treating and/or preventing depressions. The pharmaceutical composition contains an active substance presented by a selective serotonin reuptake inhibitor (SSRI) specified in a group of fluoxetine, paroxetine, citalopram, escitalopram, sertraline, fluvoxamine differing by the fact that as an active substance, it additionally contains N-acetyl-5-methoxytryptamine (melatonin) in the following proportions, mg: selective serotonin reuptake inhibitor (SSRI) - 10-30 mg, melatonin - 3-8 mg. The pharmaceutical composition may be presented by a solid dosage form - a tablet, a film-coated tablet, a capsule, by a soft dosage form - a rectal suppository.

EFFECT: pharmaceutical composition provides treating depressions and has a number of additional therapeutic properties: easing falling asleep and relieving sleeping disorders, recovering circadian rhythm and seasonal rhythm with reducing a risk of side effects of SSRI.

3 cl, 14 tbl, 7 ex

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RU 2 475 235 C2

Authors

Maksvitis Roman Jonovich

Ivanov Roman Vladimirovich

Donetskij Aleksandr Anatol'Evich

Dates

2013-02-20Published

2011-03-15Filed