USING THE ACETYLCHOLINESTERASE AND IDALOPIRDINE INHIBITOR TO REDUCE THE RISK OF FALLS IN THE PATIENTS WITH PARKINSON'S DISEASE Russian patent published in 2021 - IPC A61K31/27 A61K31/4045 A61K31/445 A61K31/55 A61K45/06 A61P25/16 A61P25/28 

Abstract RU 2742173 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: present invention relates to use of N-(2-(6-fluoro-1H-indol-3-yl)ethyl)-3-(2,2,3,3-tetrafluoropropoxy)benzylamine (idalopirdine) for preparing a drug for reducing the risk of falls in a patient suffering Parkinson's disease, wherein the treatment additionally involves the introduction of donepezil to said patient. Donepezil dose may range from 1 to 30 mg, the daily dose of idalopirdine 10 to 120 mg.

EFFECT: combination of idalopirdine and donepezil provides a significant reduction in the number of falls in Parkinson's disease.

3 cl, 7 dwg, 2 tbl, 2 ex

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RU 2 742 173 C2

Authors

De Jong, Inge, E, M

Kucinski, Aaron

Sarter, Martin

Dates

2021-02-02Published

2017-04-25Filed