MEANS FOR ORGANOTYPIC PRESERVATION OF DONOR CORNEA Russian patent published in 2021 - IPC A01N1/02 

Abstract RU 2745114 C1

FIELD: medical biology, ophthalmology.

SUBSTANCE: invention is an agent for organotypic preservation of a donor cornea, containing medium 199, Ham's F-10 medium, chondroitin sulfate, dextran, gentamicin sulfate, amphotericin B and Dulbecco-Eagle medium, according to the invention, additionally contains Cycloferon and Cymeven, and Dextran-T500 is used as dextran, with the following ratio of components, per 100 ml:

Medium 199 - 25.0 ml

Ham's medium F-10 - 25.0 ml

Chondroitin sulfate A - 0.5 g

Dextran-T500 - 5.0 g

Gentamicin sulfate - 0.00014 g

Amphotericin B - 0.00015 g

Cycloferon - 1 mg

Cymeven - 0.5 mg

Dulbecco's Modified Eagle's medium - the rest.

EFFECT: invention allows stopping replication of herpes viruses and providing effective preoperative prevention of transmission of herpes viral infection from donor to recipient due to synergistic antiviral action of the agent components.

1 cl

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RU 2 745 114 C1

Authors

Borzenok Sergej Anatolevich

Malyugin Boris Eduardovich

Kerimov Timur Zakhirovich

Izmajlova Svetlana Borisovna

Gavrilova Natalya Aleksandrovna

Kalinnikov Yurij Yurevich

Komakh Yurij Alekseevich

Khubetsova Madina Khetagovna

Dates

2021-03-22Published

2020-08-12Filed