FIELD: medicine/biotechnology.
SUBSTANCE: invention relates to the use of a compound selected from (12aR)-7-hydroxy-12-[(10S)-6,7-difluoro-5,10-dihydrothieno[3,2-c][2]benzothiepin-10-yl]-3,4,12,12а-tetrahydro-1H-[1,4]oxazino [3,4-c]pyrido[2,1-ƒ][1,2,4]triazine-6,8-dione(1.2.1) or (12aR)-7-hydroxy-12-[(10S)-7,8-difluoro-4,9-dihydrothieno[2,3-c][2]benzothiepin-4-yl]-3,4,12,12а-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-ƒ][1,2,4]triazine-6,8-dione (1.5.1) as an anti-coronavirus agent for inhibiting 2019-nCoV coronavirus. EFFECT: proposed is a new application of a compound selected from (1.2.1) and (1.5.1) as an anti-coronavirus agent for inhibiting the 2019-nCoV coronavirus.
3 cl, 4 ex
Title |
Year |
Author |
Number |
SUBSTITUTED 3,4,12,12A-TETRAHYDRO-1H-[1,4]OXAZINO[3,4-C]PYRIDO[2,1-F][1,2,4]TRIAZINE-6,8-DIONE, PHARMACEUTICAL COMPOSITION, METHODS FOR PRODUCTION AND USE THEREOF |
2019 |
- Ivashchenko Andrej Aleksandrovich
- Ivashchenko Aleksandr Vasilevich
- Mitkin Oleg Dmitrievich
|
RU2720305C1 |
ANELLATED 9-HYDROXY-1,8-DIOXO-1,3,4,8-TETRAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE-7-CARBOXAMIDES - INTEGRASE INHIBITORS, METHODS FOR PREPARING AND USING THEREOF |
2019 |
- Ivashchenko Andrej Aleksandrovich
- Ivashchenko Aleksandr Vasilevich
- Mitkin Oleg Dmitrievich
- Savchuk Nikolaj Filippovich
|
RU2717101C1 |
MACROHETEROCYCLIC NUCLEOSIDE DERIVATIVES AND ANALOGUES THEREOF, PRODUCTION AND USE |
2017 |
- Ivashchenko Aleksandr Vasilevich
- Ivashchenko Andrej Aleksandrovich
- Savchuk Nikolaj Filippovich
- Mitkin Oleg Dmitrievich
- Ivashchenko Alena Aleksandrovna
|
RU2731385C1 |
MKK4 PROTEIN KINASE INHIBITORS FOR STIMULATION OF LIVER REGENERATION OR REDUCTION OR PREVENTION OF HEPATOCYTE DEATH |
2019 |
- Praefke, Bent
- Klefekorn, Filip
- Zelig, Roland
- Albrekht, Volfgang
- Laufer, Shtefan
|
RU2788000C2 |
ANTI-RNA VIRAL, INCLUDING ANTI-CORONAVIRUS AGENT - SUBSTITUTED QUINOXALINE, PHARMACEUTICAL COMPOSITION AND APPLICATIONS |
2020 |
- Ivashchenko Andrej Aleksandrovich
- Ivashchenko Aleksandr Vasilevich
- Savchuk Nikolaj Filippovich
- Ivashchenko Alena Aleksandrovna
|
RU2744429C1 |
NUCLEOTIDES INCLUDING N-[(S)-1-CYCLOBUTOXYCARBONYL]PHOSPHORAMIDATE FRAGMENT, THEIR ANALOGS AND THEIR APPLICATION |
2017 |
- Aleksandr Vasilevich Ivashchenko
- Mitkin Oleg Dmitrievich
|
RU2659388C1 |
ANTIVIRAL COMPOSITION AND METHOD OF ITS APPLICATION |
2017 |
- Aleksandr Vasilevich Ivashchenko
- Mitkin Oleg Dmitrievich
|
RU2650610C1 |
ALKYL2-{[(2R,3S,5R)-5-(4-AMINO-2-OXO-2H-PYRIMIDINE-1-YL)- -HYDROXY- TETRAHYDRO-FURAN-2-YLMETHOXY]-PHENOXY-PHOSPHORYLAMINO}-PROPTONATES, NUCLEOSIDE INHIBITORS OF RNA-POLYMERASE HCV NS5B, METHODS FOR PRODUCING AND USING THEM |
2013 |
- Ivashchenko Aleksandr Vasil'Evich
|
RU2534613C2 |
COMPOUND BASED ON DIHYDRONAPTHYRIDINONE, METHOD OF ITS OBTAINING, AND ITS USE IN MEDICINE |
2021 |
- Zhou, Fusheng
- Xu, Xiaoming
- Zhang, Leitao
- Li, Xin
- Tang, Lili
- Lan, Jiong
|
RU2809869C1 |
PRODRUG OF POLYMERASE NS5B HCV INHIBITOR, METHOD FOR ITS PREPARATION AND APPLICATION |
2017 |
- Ivashchenko Aleksandr Vasilevich
- Mitkin Oleg Dmitrievich
|
RU2644156C1 |