ANTICORONAVIRUS THERAPEUTIC AGENT - SUBSTITUTED 7-HYDROXY-3,4,12,12A-TETRAHYDRO-1H-[1,4]OXAZINO[3,4-C]PYRIDO[2,1-F][1,2,4]TRIAZINE-6,8-DIONE FOR THE PREVENTION AND TREATMENT OF COVID-19 Russian patent published in 2021 - IPC C07D498/14 A61K31/5383 A61P31/14 

Abstract RU 2745985 C1

FIELD: medicine/biotechnology.

SUBSTANCE: invention relates to the use of a compound selected from (12aR)-7-hydroxy-12-[(10S)-6,7-difluoro-5,10-dihydrothieno[3,2-c][2]benzothiepin-10-yl]-3,4,12,12а-tetrahydro-1H-[1,4]oxazino [3,4-c]pyrido[2,1-ƒ][1,2,4]triazine-6,8-dione(1.2.1) or (12aR)-7-hydroxy-12-[(10S)-7,8-difluoro-4,9-dihydrothieno[2,3-c][2]benzothiepin-4-yl]-3,4,12,12а-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-ƒ][1,2,4]triazine-6,8-dione (1.5.1) as an anti-coronavirus agent for inhibiting 2019-nCoV coronavirus. EFFECT: proposed is a new application of a compound selected from (1.2.1) and (1.5.1) as an anti-coronavirus agent for inhibiting the 2019-nCoV coronavirus.

3 cl, 4 ex

Similar patents RU2745985C1

Title Year Author Number
SUBSTITUTED 3,4,12,12A-TETRAHYDRO-1H-[1,4]OXAZINO[3,4-C]PYRIDO[2,1-F][1,2,4]TRIAZINE-6,8-DIONE, PHARMACEUTICAL COMPOSITION, METHODS FOR PRODUCTION AND USE THEREOF 2019
  • Ivashchenko Andrej Aleksandrovich
  • Ivashchenko Aleksandr Vasilevich
  • Mitkin Oleg Dmitrievich
RU2720305C1
ANELLATED 9-HYDROXY-1,8-DIOXO-1,3,4,8-TETRAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE-7-CARBOXAMIDES - INTEGRASE INHIBITORS, METHODS FOR PREPARING AND USING THEREOF 2019
  • Ivashchenko Andrej Aleksandrovich
  • Ivashchenko Aleksandr Vasilevich
  • Mitkin Oleg Dmitrievich
  • Savchuk Nikolaj Filippovich
RU2717101C1
MACROHETEROCYCLIC NUCLEOSIDE DERIVATIVES AND ANALOGUES THEREOF, PRODUCTION AND USE 2017
  • Ivashchenko Aleksandr Vasilevich
  • Ivashchenko Andrej Aleksandrovich
  • Savchuk Nikolaj Filippovich
  • Mitkin Oleg Dmitrievich
  • Ivashchenko Alena Aleksandrovna
RU2731385C1
MKK4 PROTEIN KINASE INHIBITORS FOR STIMULATION OF LIVER REGENERATION OR REDUCTION OR PREVENTION OF HEPATOCYTE DEATH 2019
  • Praefke, Bent
  • Klefekorn, Filip
  • Zelig, Roland
  • Albrekht, Volfgang
  • Laufer, Shtefan
RU2788000C2
ANTI-RNA VIRAL, INCLUDING ANTI-CORONAVIRUS AGENT - SUBSTITUTED QUINOXALINE, PHARMACEUTICAL COMPOSITION AND APPLICATIONS 2020
  • Ivashchenko Andrej Aleksandrovich
  • Ivashchenko Aleksandr Vasilevich
  • Savchuk Nikolaj Filippovich
  • Ivashchenko Alena Aleksandrovna
RU2744429C1
NUCLEOTIDES INCLUDING N-[(S)-1-CYCLOBUTOXYCARBONYL]PHOSPHORAMIDATE FRAGMENT, THEIR ANALOGS AND THEIR APPLICATION 2017
  • Aleksandr Vasilevich Ivashchenko
  • Mitkin Oleg Dmitrievich
RU2659388C1
ANTIVIRAL COMPOSITION AND METHOD OF ITS APPLICATION 2017
  • Aleksandr Vasilevich Ivashchenko
  • Mitkin Oleg Dmitrievich
RU2650610C1
ALKYL2-{[(2R,3S,5R)-5-(4-AMINO-2-OXO-2H-PYRIMIDINE-1-YL)- -HYDROXY- TETRAHYDRO-FURAN-2-YLMETHOXY]-PHENOXY-PHOSPHORYLAMINO}-PROPTONATES, NUCLEOSIDE INHIBITORS OF RNA-POLYMERASE HCV NS5B, METHODS FOR PRODUCING AND USING THEM 2013
  • Ivashchenko Aleksandr Vasil'Evich
RU2534613C2
COMPOUND BASED ON DIHYDRONAPTHYRIDINONE, METHOD OF ITS OBTAINING, AND ITS USE IN MEDICINE 2021
  • Zhou, Fusheng
  • Xu, Xiaoming
  • Zhang, Leitao
  • Li, Xin
  • Tang, Lili
  • Lan, Jiong
RU2809869C1
PRODRUG OF POLYMERASE NS5B HCV INHIBITOR, METHOD FOR ITS PREPARATION AND APPLICATION 2017
  • Ivashchenko Aleksandr Vasilevich
  • Mitkin Oleg Dmitrievich
RU2644156C1

RU 2 745 985 C1

Authors

Ivashchenko Andrej Aleksandrovich

Ivashchenko Aleksandr Vasilevich

Mitkin Oleg Dmitrievich

Dates

2021-04-05Published

2020-05-07Filed