METHOD OF OBTAINING EPOPROSTENOL SODIUM OF INCREASED STABILITY Russian patent published in 2021 - IPC C07D307/77 A61K31/343 A61P11/00 A61P9/12 A61K9/19 

Abstract RU 2747646 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a composition based on stable epoprostenol sodium, which has a vasodilating and inhibitory effect on platelet aggregation, which consists of the sodium salt of epoprostenol and sodium hydroxide in a ratio of 3-7.5 g of sodium hydroxide per 100 g of the sodium salt of epoprostenol, as well as a method for its preparation.

EFFECT: new stable composition based on sodium epoprostenol has been obtained, which can be stored in a low-temperature freezer (-20±5°C) for at least 3 years.

8 cl, 2 ex

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RU 2 747 646 C2

Authors

Hortobagyi, Iren

Laszlofi, Istvan

Kardos, Zsuzsanna

Molnar, Jozsef

Takacs, Laszlo

Tormasi, Robertne

Dates

2021-05-11Published

2017-03-21Filed