FIELD: immunology.
SUBSTANCE: present invention relates to the field of immunology. An immunoreactive cell for cancer treatment expressing a second-generation chimeric antigen receptor and a chimeric costimulating receptor has been proposed. In addition, a method for producing an immunoreactive cell, a combination of nucleic acids, a vector, a combination of vectors, and a method for stimulating the immune response have been considered.
EFFECT: invention may find further application in treatment of various types of cancer.
20 cl, 25 dwg, 4 ex
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