AQUEOUS SUSPENSION CONTAINING GLUCOCORTICOSTEROID NANOPARTICLES Russian patent published in 2021 - IPC A61K9/10 A61K31/573 A61K47/10 A61K47/12 A61K47/24 A61K47/32 A61K47/34 A61K47/38 A61P29/00 A61P31/00 

Abstract RU 2747803 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: group of inventions relates to the field of medicine and pharmaceuticals. Object 1 is an aqueous suspension for the treatment or prevention of an inflammatory or infectious disease containing nanoparticles of a glucocorticosteroid compound, a physiologically acceptable salt, glycerin, hydrogenated soy lecithin, and anhydrous citric acid. Objects 2 and 3 are the corresponding pharmaceutical composition and a set for obtaining a pharmaceutical composition. Object 4 is a method for making a pharmaceutical composition, including mixing a glucocorticosteroid compound, a physiologically acceptable salt, glycerol, hydrogenated soy lecithin, anhydrous citric acid and water.

EFFECT: stability of the storage properties and the stability of the dispersion of the suspension and pharmaceutical composition containing nanoparticles of a low-size glucocorticosteroid compound as the active component, due to the use of nanoparticles of a glucocorticosteroid compound, a physiologically acceptable salt, glycerol, hydrogenated soy lecithin and anhydrous citric acid.

21 cl, 13 dwg, 11 tbl, 13 ex

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RU 2 747 803 C2

Authors

Tada, Takahiro

Kagami, Kazuhiro

Kikuchi, Kenta

Dates

2021-05-14Published

2016-05-09Filed