FIELD: medicine.
SUBSTANCE: ophthalmological composition of water-based suspension for local application contains caboxylvinyl polymer in concentration from 0.1 to 0.5% (wt/vol), galactomannan in concentration from 0.1 to 0.4% (wt/vol), borate in concentration from 0.4 to 2.0% (wt/vol) and sparingly soluble compound in form of particles, representing nepafenacum in concentration from 0.25 to 0.35% (wt/vol). Said compound possesses water solubility at 25°C from 0.001 to 0.1% (wt/vol) and particle size from 50 to 70 nm.
EFFECT: support of composition viscosity in introduction into eye and good bioavailability of sparingly soluble active substances.
17 cl, 2 tbl, 5 dwg, 4 ex
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