AMINO-ACID DERIVATIVE OF THE DECAHYDRO-CLOSO-DECABORATE ANION AND ITS ANTIVIRAL ACTIVITY AGAINST INFLUENZA A VIRUS Russian patent published in 2021 - IPC C07D233/64 C07F5/02 C01B35/18 A61K31/4172 

Abstract RU 2749006 C1

FIELD: virology; medicine.

SUBSTANCE: invention relates to virology and medicine, namely to the amino-acid derivative of the decahydro-closo-decaborate anion (Na2[B10H9OCH2CH2CH2CH2CO-His-OMe]), where the anion part is represented by the formula (I).

EFFECT: compound Na2[B10H9-O(CH2)4CO-His-OMe] inhibits the reproduction of the influenza A virus, including strains resistant to adamantane-type drugs.

2 cl, 3 dwg, 3 ex

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RU 2 749 006 C1

Authors

Garaev Timur Mansurovich

Grebennikova Tatyana Vladimirovna

Avdeeva Varvara Vladimirovna

Malinina Elena Anatolevna

Kuznetsov Nikolaj Timofeevich

Zhizhin Konstantin Yurevich

Breslav Natalya Vladimirovna

Zhdanov Andrej Petrovich

Burtseva Elena Ivanovna

Dates

2021-06-02Published

2020-11-27Filed