FIELD: medicine.
SUBSTANCE: invention relates to medicine, specifically to new chemical compounds – 3-substituted 6-(methoxycarbonyl)umbelliferones of below structural formula (Ia,b), in which the substitute in position C-3 of coumarin is represented by fragments of methyl ester of 11-[(1H-1,2,3-triazol-4-yl)methylamino]undecanoic acid or methyl ester of 6-aminopenicylanic acid. Disclosed compound of formula (Ia,b) has the ability to inhibit influenza virus A/Puerto Rico/8/34 (H1N1).
EFFECT: more effective suppression of reproduction of influenza virus and wider range of inhibitors of reproduction of influenza virus.
1 cl, 2 dwg, 1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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|
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| IMINE DERIVATIVES OF CAMPHOR, CONTAINING AROMATIC OR HETEROAROMATIC FRAGMENT - INHIBITORS OF REPRODUCTION OF FLU VIRUS (STRAIN A/CALIFORNIA/07/09(H1N1)pdm09) | 2015 |
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| USING 1,7,7-TRIMETHYLBICYCLO[2,2,1]HEPTAN-2-YLIDENE-AMINOETHANOL AS INFLUENZA VIRUS REPRODUCTION INHIBITOR | 2013 |
|
RU2530554C1 |
| (1S,3aR,4R,7aS)-N-(2,2,4,7a-TETRAMETHYLOCTAHYDRO-1,4-ETHANOINDENE-3a-YL)-ACETAMIDE APPLICATION AS A INFLUENZA VIRUS REPRODUCTION INHIBITOR | 2016 |
|
RU2616255C1 |
| APPLICATION OF ALIPHATIC IMINO-DERIVATIVES OF CAMPFOR AS EFFECTIVE INHIBITORS OF REPRODUCTION OF INFLUENZA VIRUS STRAIN A/CALIFORNIA/07/09 (H1N1) PDM09 AND A/PUERTO RICO/8/34 (H1N1) | 2016 |
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RU2651754C1 |
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