SYMMETRIC DIIMINES BASED ON CAMPHOR - INHIBITORS OF REPRODUCTION OF INFLUENZA VIRUS (STRAIN A/California/07/09 (H1N1)pdm09) Russian patent published in 2014 - IPC C07C211/50 C07C211/41 C07C217/90 A61P31/16 

Abstract RU 2520967 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to new symmetrical diimines based on camphor of general formula 1a-f, which are inhibitors of influenza virus reproduction (strain A/California/07/09 (H1N1) pdm09). In the general formula 1a-f The compounds along with pronounced antiviral activity against the said influenza virus have low toxicity.

EFFECT: chemotherapeutic index exceeds that of the known reference preparations three or more times.

1 tbl, 8 ex

Similar patents RU2520967C1

Title Year Author Number
METHOD OF PRODUCING SYMMETRICAL CAMPHOR-BASED DIIMINES 2023
  • Burmistrov Vladimir Vladimirovich
  • Zapravdina Daria Mikhailovna
RU2821532C1
COMPOUND 6,8-DIFLUORO-2-(4-(TRIFLUOROMETHYL)PHENYL)CHROMAN-4-ONE AS INHIBITOR OF REPRODUCTION OF INFLUENZA A AND B VIRUSES AND METHOD FOR PRODUCTION THEREOF 2023
  • Politanskaya Larisa Vladimirovna
  • Troshkova Nadezhda Mikhajlovna
  • Zarubaev Vladimir Viktorovich
  • Esaulkova Yana Leonidovna
  • Volobueva Aleksandrina Sergeevna
RU2826250C1
IMINE COMPOUNDS OF CAMPHOR - EFFECTIVE INHIBITORS OF REPRODUCTION OF FLU VIRUS (A/California/07/09 (H1N1)pdm09 STRAIN) 2014
  • Sokolova Anastasija Sergeevna
  • Jarovaja Ol'Ga Ivanovna
  • Shernjukov Andrej Vladimirovich
  • Tretjak Tat'Jana Sergeevna
  • Zarubaev Vladimir Viktorovich
  • Kiselev Oleg Ivanovich
  • Salakhutdinov Nariman Faridovich
RU2554934C1
SUBSTITUTED OCTAHYDROCHROMENES AS AN ANTIVIRAL AGENT 2017
  • Ilina Irina Viktorovna
  • Volcho Konstantin Petrovich
  • Zarubaev Vladimir Viktorovich
  • Salakhutdinov Nariman Faridovich
RU2664728C1
AGENT FOR INHIBITING HUMAN ENZYME TYROSYL-DNA-PHOSPHODIESTERASE 1 BASED ON PHENYLCOUMARINES, SENSITIZING TUMORS TO ANTITUMOUR AGENTS 2019
  • Khomenko Tatyana Mikhajlovna
  • Zakharenko Aleksandra Leonidovna
  • Cherepanova Arina Aleksandrovna
  • Ilina Ekaterina Sergeevna
  • Zakharova Olga Dmitrievna
  • Kaledin Vasilij Ivanovich
  • Nikolin Valerij Petrovich
  • Popova Nelli Aleksandrovna
  • Volcho Konstantin Petrovich
  • Lavrik Olga Ivanovna
  • Salakhutdinov Nariman Faridovich
RU2724878C1
(1S,3aR,4R,7aS)-N-(2,2,4,7a-TETRAMETHYLOCTAHYDRO-1,4-ETHANOINDENE-3a-YL)-ACETAMIDE APPLICATION AS A INFLUENZA VIRUS REPRODUCTION INHIBITOR 2016
  • Yarovaya Olga Ivanovna
  • Shtro Anna Andreevna
  • Orshanskaya Yana Rafaelevna
  • Zarubaev Vladimir Viktorovich
  • Khazanov Veniamin Abramovich
  • Salakhutdinov Nariman Faridovich
RU2616255C1
MEANS FOR HUMAN TYROSYL-DNA-PHOSPHODIESTERASE 1 ENZYME INHIBITION 2015
RU2612875C1
IMINE DERIVATIVES OF CAMPHOR, CONTAINING AROMATIC OR HETEROAROMATIC FRAGMENT - INHIBITORS OF REPRODUCTION OF FLU VIRUS (STRAIN A/CALIFORNIA/07/09(H1N1)pdm09) 2015
  • Yarovaya Olga Ivanovna
  • Sokolova Anastasiya Sergeevna
  • Shernyukov Andrej Vladimirovich
  • Tretyak Tatyana Sergeevna
  • Zarubaev Vladimir Viktorovich
  • Belskij Yurij Pavlovich
  • Belskaya Nataliya Vitalevna
  • Kiselev Oleg Ivanovich
  • Khazanov Veniamin Abramovich
  • Salakhutdinov Nariman Faridovich
RU2607451C1
LABDANE-TYPE 6-HYDROXYNAPHTHOQUINONES, HAVING CYTOTOXIC ACTIVITY ON HUMAN TUMOUR CELLS 2012
  • Shul'Ts Ehl'Vira Ehduardovna
  • Mironov Maksim Evgen'Evich
  • Pokrovskij Mikhail Andreevich
  • Sherman Ksenija Mikhajlovna
  • Pokrovskij Andrej Georgievich
  • Tolstikov Genrikh Aleksandrovich
RU2479582C1
USING 1,7,7-TRIMETHYLBICYCLO[2,2,1]HEPTAN-2-YLIDENE-AMINOETHANOL AS INFLUENZA VIRUS REPRODUCTION INHIBITOR 2013
  • Jarovaja Ol'Ga Ivanovna
  • Sokolova Anastasija Sergeevna
  • Tretjak Tat'Jana Sergeevna
  • Zarubaev Vladimir Viktorovich
  • Kiselev Oleg Ivanovich
  • Salakhutdinov Nariman Faridovich
RU2530554C1

RU 2 520 967 C1

Authors

Sokolova Anastasija Sergeevna

Jarovaja Ol'Ga Ivanovna

Salakhutdinov Nariman Faridovich

Kiselev Oleg Ivanovich

Zarubaev Vladimir Viktorovich

Tretjak Tat'Jana Sergeevna

Dates

2014-06-27Published

2013-02-08Filed