DENTAL GEL Russian patent published in 2021 - IPC A61K9/10 A61K31/155 A61K31/167 A61K31/375 A61K35/60 A61K36/61 A61K36/76 A61K47/10 A61K47/26 A61P1/02 

Abstract RU 2749713 C1

FIELD: medicine; pharmacy.

SUBSTANCE: invention relates to the field of medicine and pharmacy, in particular, to the development of a therapeutic and prophylactic agent in the form of a dental gel for the treatment and prevention of infectious and inflammatory diseases of the oral mucosa. The proposed gel contains dry extract of white willow bark, essential oil of Eucalyptus prutoid, ascorbic acid, lidocaine hydrochloride, chlorhexidine bigluconate, sorbitol, nipagin (methylparaben). When obtaining the product, collagen-containing raw materials of fish origin (fish gelatin), glycerin and purified water are used as a gel base with the following ratio of components, wt. %: dry extract of white willow bark - 8.0-10.0; essential oil of Eucalyptus rod-shaped - 0.05-0.1; ascorbic acid - 2.0-4.0; lidocaine hydrochloride - 3.0-4.0; chlorhexidine bigluconate - 3.0-4.0; collagen-containing raw materials of fish origin - 30.0-40.0; glycerin - 1.0-2.0; sorbitol - 3.0-4.0; nipagin - 0.3-0.5; purified water - the rest.

EFFECT: composition of the gel ensures its good fixation and uniform distribution on the mucous membrane of the oral cavity, a fairly rapid release of the complex of active components, the invention is characterized by optimal technological and biopharmaceutical characteristics that cause anti-inflammatory, immunotropic and antimicrobial action throughout the entire period of storage and use.

1 cl, 2 tbl, 6 ex

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RU 2 749 713 C1

Authors

Polukhina Tatyana Sergeevna

Yakubova Olesya Sergeevna

Bekesheva Adelya Adlerovna

Tsibizova Aleksandra Aleksandrovna

Salnikova Natalya Alekseevna

Bashkina Olga Aleksandrovna

Nevalennyj Aleksandr Nikolaevich

Rubalskij Oleg Vasilevich

Maksimenko Yurij Aleksandrovich

Dates

2021-06-16Published

2020-07-29Filed