FIELD: medicine; pharmacy.
SUBSTANCE: invention relates to the field of medicine and pharmacy, in particular, to the development of a therapeutic and prophylactic agent in the form of a dental gel for the treatment and prevention of infectious and inflammatory diseases of the oral mucosa. The proposed gel contains dry extract of white willow bark, essential oil of Eucalyptus prutoid, ascorbic acid, lidocaine hydrochloride, chlorhexidine bigluconate, sorbitol, nipagin (methylparaben). When obtaining the product, collagen-containing raw materials of fish origin (fish gelatin), glycerin and purified water are used as a gel base with the following ratio of components, wt. %: dry extract of white willow bark - 8.0-10.0; essential oil of Eucalyptus rod-shaped - 0.05-0.1; ascorbic acid - 2.0-4.0; lidocaine hydrochloride - 3.0-4.0; chlorhexidine bigluconate - 3.0-4.0; collagen-containing raw materials of fish origin - 30.0-40.0; glycerin - 1.0-2.0; sorbitol - 3.0-4.0; nipagin - 0.3-0.5; purified water - the rest.
EFFECT: composition of the gel ensures its good fixation and uniform distribution on the mucous membrane of the oral cavity, a fairly rapid release of the complex of active components, the invention is characterized by optimal technological and biopharmaceutical characteristics that cause anti-inflammatory, immunotropic and antimicrobial action throughout the entire period of storage and use.
1 cl, 2 tbl, 6 ex
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Authors
Dates
2021-06-16—Published
2020-07-29—Filed