FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology. A computer-implemented method for the joint determination of variants in homologous regions is proposed. The method includes identifying one or more homologous regions to be co-processed, loading a co-cluster for the regions to be co-processed, creating a list of candidate variants from the co-cluster and creating a connectivity matrix that determines the order of processing the positions of candidate variants, determining the position of the candidate variant from the final genotype matrix, and outputting a variant definition file.
EFFECT: invention provides improved accuracy of the data obtained from the sequence.
9 cl, 80 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| BIOINFORMATION SYSTEMS, DEVICES AND METHODS FOR SECONDARY AND/OR TERTIARY PROCESSING | 2017 |
|
RU2799750C2 |
| GENOMIC INFRASTRUCTURE FOR LOCAL AND CLOUD PROCESSING AND ANALYSIS OF DNA AND RNA | 2017 |
|
RU2804029C2 |
| GENOMIC INFRASTRUCTURE FOR LOCAL AND CLOUD PROCESSING AND ANALYSIS OF DNA AND RNA | 2017 |
|
RU2761066C2 |
| WHOLE GENOME SEQUENCING DATA PROCESSING SYSTEM | 2023 |
|
RU2806429C1 |
| WHOLE GENOME SEQUENCING DATA PROCESSING SYSTEM | 2023 |
|
RU2804535C1 |
| METHOD AND SYSTEM FOR DETERMINING NUCLEOTIDE SEQUENCE IN GIVEN REGION OF FOETAL GENOME | 2012 |
|
RU2597981C2 |
| METHODS AND SYSTEMS FOR OBTAINING SETS OF UNIQUE MOLECULAR INDICES WITH HETEROGENEOUS LENGTH OF MOLECULES AND CORRECTING ERRORS THEREIN | 2018 |
|
RU2766198C2 |
| MOLECULAR MARKERS ASSOCIATED WITH SUNFLOWER RESISTANCE TO OROBANCHE | 2018 |
|
RU2776361C2 |
| SPLICING SITES CLASSIFICATION BASED ON DEEP LEARNING | 2018 |
|
RU2780442C2 |
| A DEEP LEARNING FRAME FOR IDENTIFYING SEQUENCE PATTERNS THAT CAUSE SEQUENCE SPECIFIC ERRORS (SSE) | 2019 |
|
RU2745733C1 |
