METHOD FOR DIFFERENTIAL DIAGNOSIS OF LIVER STEATOSIS AND NON-ALCOHOLIC STEATOHEPATITIS IN MEN Russian patent published in 2021 - IPC A61B5/00 G01N33/92 G01N30/72 

Abstract RU 2753455 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine and deals with a method for the differential diagnosis of liver steatosis and non-alcoholic steatohepatitis in men. The essence of the method is that the ratio of the concentration of 3-hydroxybutyric and 3-methyl-2-oxovaleric acids determined by chromatographic method in a patient's venous blood sample is determined. When the ratio of the concentration of 3-hydroxybutyric acid to the concentration of 3-methyl-2-oxovaleric acid is 19/1 or more, liver steatosis is diagnosed, with a ratio of 13/1 or less, NASH is diagnosed.

EFFECT: method can be used for non-invasive determination of liver steatosis and non-alcoholic steatohepatitis in male patients with non-alcoholic fatty liver disease.

1 cl, 5 dwg, 3 tbl, 2 ex

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RU 2 753 455 C1

Authors

Demianova Elena Valerevna

Abatsieva Madina Petrovna

Sitkin Stanislav Igorevich

Vakhitov Timur Iasherovich

Bakulin Igor Gennadevich

Shcherbakova Elena Sergeevna

Sall Tatiana Sergeevna

Dates

2021-08-16Published

2020-12-11Filed