FIELD: pharmaceuticals.
SUBSTANCE: invention relates to the field of pharmaceuticals, namely to an application of a recombinant analogue of the HCRG21 peptide as an active pharmaceutical substance for creating a medicinal product exhibiting a prolonged analgesic, anti-inflammatory effect, and effectively reducing the body temperature in animals and humans.
EFFECT: invention provides a longer-lasting analgesic effect, mitigation of inflammation, a more pronounced hypothermic effect when applying the recombinant analogue of the peptide HCRG21 as an active pharmaceutical substance for alleviating pain conditions, mitigating inflammation and reducing the body temperature in humans and animals on parenteral or intranasal administration.
2 cl, 11 dwg, 1 tbl, 11 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ANALGESIC PEPTIDE OF SEA ANEMONE | 2016 |
|
RU2614759C1 |
| ACTINIA POLYPEPTIDE HAVING ANALGETIC ACTION | 2008 |
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RU2368621C1 |
| ACTINIA POLYPEPTIDE, POSSESSING ANALGESIC ACTION | 2009 |
|
RU2404245C1 |
| WATER-SOLUBLE TYROSINE DERIVATIVES HAVING ANALGESIC, ANTI-INFLAMMATORY AND ANTIEDEMIC ACTION | 2017 |
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RU2678563C1 |
| TYROSINE HETEROCYCLIC AMIDES, HAVING ANALGESIC, ANTI-INFLAMMATORY AND ANTIEDEMIC ACTION | 2018 |
|
RU2685505C1 |
| PHARMACEUTICAL COMPOSITIONS OF THIOCHROMENOL BASED ON A HEXAHYDRO-HETEROCYCLIC COMPOUND WITH ANALGESIC EFFECT, AND METHODS FOR THEIR USE IN DOMESTIC AND FARM ANIMALS | 2022 |
|
RU2812294C2 |
| QUINAZOLIN-4(3H)-ONE DIMETHOXYBENZYLSULFO DERIVATIVE WITH ANALGESIC, ANTIPARKINSONIAN, ANXIOLYTIC, PSYCHOSTIMULATING ACTIVITY | 2021 |
|
RU2758333C1 |
| 4-(3,4-DIBROMOTHYOPHENE CARBONYL)-2,6,8,10,12-PENTAACETYL-2,4,6,8,10,12 HEXAAZAISOWURTZITANE AS AN ANALGESIC AGENT AND METHOD FOR ITS PREPARATION | 2021 |
|
RU2769523C1 |
| ANALGETIC, ANTIPYRETIC AND ANTI-INFLAMMATORY AGENT "PENTABUFEN" | 2002 |
|
RU2222322C1 |
| 6-(3,3-DIMETHYL-3,4-DIHYDROISOCHINOLIN-1-IL) AMINOHEXANE ACID AND PHARMACEUTICAL COMPOSITION ON ITS BASIS THAT HAVE ANALGETIC ACTIVITY | 2016 |
|
RU2648445C1 |
