FIELD: pharmaceutics.
SUBSTANCE: invention relates to a new chemical substance: 4-(3,4-dibromothyophene carbonyl)-2,6,8,10,12-pentaacetyl-2,4,6,8,10,12 hexaazaisowurtzitane (I), as well as to a method for its preparation, which consists in the acylation of 4-(3,4-dibromothyophencarbonyl)-2,6,8,12-tetraacetyl-2,4,6,8,10,12- hexaazaisowurtzitane with acetyl chloride.
EFFECT: a new compound 4-(3,4-dibromothyophene carbonyl)-2,6,8,10,12-pentaaacetyl-2,4,6,8,10,12 hexaazaisowurtzitane with analgesic activity comparable to and/or superior to the effectiveness of Tramadol was obtained.
2 cl, 4 tbl, 2 ex
| Title |
Year |
Author |
Number |
| 4-(3,4-DIBROMOTHIOPHENE CARBONYL)-10-(2-ETHOXYACETYL)-2,6,8,12-TETRAACETYL-2,4,6,8,10,12-HEXAAZATETRACYCLO[5,5,0,0,0]DODECANE AS AN ANALGESIC AGENT AND METHOD FOR PRODUCTION THEREOF |
2021 |
- Krylova Svetlana Gennadevna
- Poveteva Tatyana Nikolaevna
- Suslov Nikolaj Innokentevich
- Zueva Elena Petrovna
- Nesterova Yuliya Vladimirovna
- Afanaseva Olga Gennadevna
- Kulpin Pavel Valerevich
- Kiseleva Elena Andreevna
- Amosova Evdokiya Naumovna
- Razina Tatyana Georgievna
- Rybalkina Olga Yurevna
- Safonova Elena Andreevna
- Zhdanov Vadim Vadimovich
- Kalashnikov Aleksandr Ivanovich
- Bajbakova Olga Vladimirovna
- Bakholdina Lyubov Alekseevna
- Eremina Valeriya Valerevna
- Kulagina Darya Aleksandrovna
- Alekseeva Natalya Alekseevna
- Sysolyatin Sergej Viktorovich
|
RU2786231C1 |
| 4-(2-ETOXYACETYL)-2,6,8,10,12-PENTAACETYL-2,4,6,8,10,12-HEXAAZATETRACYCLO [5,5,0,0,0] DODECANE AS ANALGETIC AND METHOD OF ITS OBTAINING |
2023 |
- Krylova Svetlana Gennadevna
- Poveteva Tatyana Nikolaevna
- Suslov Nikolaj Innokentevich
- Zueva Elena Petrovna
- Nesterova Yuliya Vladimirovna
- Afanaseva Olga Gennadevna
- Kulpin Pavel Valerevich
- Kiseleva Elena Aleksandrovna
- Rybalkina Olga Yurevna
- Zhdanov Vadim Vadimovich
- Bajbakova Olga Vladimirovna
- Eremina Valeriya Valerevna
- Kulagina Darya Aleksandrovna
- Alekseeva Natalya Alekseevna
- Chikina Majya Viktorovna
- Sysolyatin Sergej Viktorovich
|
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| 4,10-DI(ETHOXYACETYL)-2,6,8,12-TETRAACETYL-2,4,6,8,10,12-HEXAAZATETRACYCLO[5,5,0,0,0] DODECANE AS AN ANALGESIC AGENT AND A METHOD FOR PRODUCTION THEREOF |
2020 |
- Krylova Svetlana Gennadevna
- Poveteva Tatyana Nikolaevna
- Suslov Nikolaj Innokentevich
- Zueva Elena Petrovna
- Nesterova Yuliya Vladimirovna
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- Eremina Valeriya Valerevna
- Sonina Ekaterina Georgievna
- Kulagina Darya Aleksandrovna
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|
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2014 |
- Krylova Svetlana Gennad'Evna
- Amosova Evdokija Naumovna
- Zueva Elena Petrovna
- Razina Tat'Jana Georgievna
- Rybalkina Ol'Ga Jur'Evna
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- Malykhin Valerij Viktorovich
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- Vorozhtsov Aleksandr Borisovich
- Zhukov Aleksandr Stepanovich
|
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2018 |
- Krylova Svetlana Gennadevna
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- Sysolyatin Sergej Viktorovich
- Suslov Nikolaj Innokentevich
- Zueva Elena Petrovna
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- Zhdanov Vadim Vadimovich
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2014 |
- Krylova Svetlana Gennad'Evna
- Amosova Evdokija Naumovna
- Zueva Elena Petrovna
- Razina Tat'Jana Georgievna
- Rybalkina Ol'Ga Jur'Evna
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2022 |
- Krylova Svetlana Gennadevna
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- Poveteva Tatyana Nikolaevna
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- Eremina Valeriya Valerevna
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- Aksinenko Svetlana Gennadevna
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