ANALYTICAL SYSTEM FOR DIAGNOSING LUNG CANCER USING FREE AND CIRCULATING MICRO-RNAS ASSOCIATED WITH BLOOD CELLS Russian patent published in 2021 - IPC G01N33/58 G01N33/574 C12Q1/686 C12Q1/6876 

Abstract RU 2755651 C1

FIELD: medicine.

SUBSTANCE: proposed group of inventions relates to the field of medicine, in particular to molecular genetic diagnostics. A method and analytical system for the diagnosis of lung cancer are proposed, including primers and TaqMan probes for sequences of 7 combinations of 10 micro-RNAs: miR-107/miR-222-3p, miR-19b-3p/miR-484, miR-150-5p/miR-144-5p, miR-484/miR-374a-5p, miR-484/miR-324-5p, miR-22-5p/miR-324-5p, miR-374a-5p/miR-133b.

EFFECT: proposed group of inventions provides development of a method for the differential diagnosis of malignant lung tumors with 100% sensitivity, specificity and accuracy.

3 cl, 8 tbl, 30 ex

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RU 2 755 651 C1

Authors

Konoshenko Mariya Yurevna

Bryzgunova Olga Evgenevna

Zaporozhchenko Ivan Andreevich

Zheravin Aleksandr Aleksandrovich

Laktionov Pavel Petrovich

Lantsukhaj Yurij Aleksandrovich

Dates

2021-09-17Published

2020-12-21Filed