COMBINATIONS AND METHODS FOR ADMINISTRATION OF THERAPEUTIC AGENTS AND COMBINATION THERAPY Russian patent published in 2018 - IPC A61K45/06 A61P35/00 A61P35/04

Abstract RU 2673805 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine and is intended for the treatment of cancer. Method uses composition containing paclitaxel and albumin, and an anti-VEGF antibody, where the effective amount of paclitaxel in the nanoparticle-containing composition ranges from about 45 mg/m² up to about 350 mg/m² and the effective amount of the anti-VEGF antibody ranges from more than 1 mg/kg to less than 10 mg/kg.

EFFECT: method allows to reduce side effects and increase the effectiveness of treatment.

17 cl, 9 tbl, 32 ex, 19 dwg

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RU 2 673 805 C2

Authors

Disej Nejl P.

Soon-Shiong Patrik

Dates

2018-11-30—Published

2013-11-05—Filed