FIELD: medicine.
SUBSTANCE: invention relates to a method for the treatment of cochlear synaptopathy, a method for the treatment of hearing loss as a result of the loss of afferent synapses of internal hair cells, a method for the treatment of tinnitus as a result of the loss of afferent synapses of internal hair cells and a method for the treatment of hearing loss in a patient who demonstrates a normal ABR threshold and/or normal DPOAE, which include the injection of therapeutically effective amount of a compound selected from a group, consisting of (S)-1-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-ilcarbamoyl)ethyl ether of (2,2,3,3,3-pentafluoropropyl)-carbamino acid, (2R)-2-fluoro-2-methyl-N-[(S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-N'-(2,2,3,3,3-pentafluoropropyl)malonamide,
, 
, and 
, or pharmaceutically acceptable salt of any of the above-mentioned compounds.
EFFECT: obtaining a method for the treatment of cochlear synaptopathy.
24 cl, 23 dwg, 7 ex
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