FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology. A peptide with the ability to specifically bind to the immune response control molecule CTLA-4 and block its interaction with the B7-1 ligand (CD80) is proposed. The peptide has the chemical formula C75H103N23O19S1 and consists of 14 amino acid residues ARHPSWYRPFEGCG.
EFFECT: invention can be used in the development of immunotropic drugs, to regulate the mechanisms of immunosuppression and activation (and proliferation) of T-lymphocytes, as well as to evaluate the expression of the CTLA-4 receptor in patients, including HIV.
1 cl, 5 dwg, 3 ex
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