FIELD: biotechnology.
SUBSTANCE: invention is related to peptide antagonists B7-2 (CD 28). A peptide is proposed that specifically interacts with the human immune response control molecule B7-2 (CD86), regulating the interaction with the costimulatory molecule CD28, selected from a cyclic peptide with the amino acid sequence CLARSLGRC or CH2-LARSLGR-CH2.
EFFECT: peptide can serve as a basis for the development of agents that regulate the immune response, as well as the creation of effective dosage forms of peptide drugs as a means of treating cancer.
1 cl, 3 dwg, 4 ex
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