PEPTIDE THAT SPECIFICALLY INTERACTS WITH THE HUMAN IMMUNE RESPONSE CONTROL MOLECULE B7-2 (CD86) Russian patent published in 2023 - IPC C07K7/06 A61K38/08 A61P35/00 

Abstract RU 2808419 C1

FIELD: biotechnology.

SUBSTANCE: invention is related to peptide antagonists B7-2 (CD 28). A peptide is proposed that specifically interacts with the human immune response control molecule B7-2 (CD86), regulating the interaction with the costimulatory molecule CD28, selected from a cyclic peptide with the amino acid sequence CLARSLGRC or CH2-LARSLGR-CH2.

EFFECT: peptide can serve as a basis for the development of agents that regulate the immune response, as well as the creation of effective dosage forms of peptide drugs as a means of treating cancer.

1 cl, 3 dwg, 4 ex

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Authors

Kolosova Evgeniya Andreevna

Viktorina Olesya Evgenevna

Shcherbakov Dmitrij Nikolaevich

Shapoval Andrej Ivanovich

Dates

2023-11-28Published

2022-11-29Filed