SYSTEM FOR CONTROLLING THE COURSE OF DIABETES WITH AUTOMATIC CONTROL OF BASAL ADMINISTRATION OF INSULIN AND MANUAL CONTROL OF BOLUS ADMINISTRATION OF INSULIN Russian patent published in 2021 - IPC A61M5/31 

FIELD: medical equipment.

SUBSTANCE: group of inventions relates to medicine, namely to systems for controlling delivery of insulin. Proposed is a system for implementing the method, wherein the system comprises: a delivery apparatus delivering insulin to the subject; a glucose sensor for measuring the glucose levels in the subject; a bolus calculator for determining the manually administered bolus dose of insulin based on the physiological data of the subject; and a controller configured to: periodically receive the glucose levels of the subject from the glucose sensor, automatically calculate the basal dose of insulin using a model predictive control (MPC) algorithm and the physiological data of the subject, including the necessary glucose levels, the amount of delivered insulin and the measured glucose levels in the subject, receive the manually administered bolus dose of insulin calculated using the bolus calculator or initiated by the subject manually, predict, using the MPC algorithm, whether there will be a glycemic jump in the subject in the near future, based on the physiological data, including the rate of change in the glucose level in the subject, indicating hypoglycemia, modify the manually administered bolus dose of insulin based on determination of a glycemic jump predicted in the near future using the MPC algorithm, including the rate of change in the glucose level in the subject, indicating hypoglycemia, modify the manually administered bolus dose of insulin based on the determination of a glycemic jump predicted in the near future using the MPC algorithm, including the rate of change in the glucose level in the subject, indicating hypoglycemia, determine the total dose of insulin based on the modified manually administered bolus dose of insulin and the calculated basal insulin dose, and deliver the total dose of insulin to the subject.

EFFECT: group of inventions provides an increase in the efficiency of controlling administration of insulin.

12 cl, 3 dwg