COMPOSITIONS AND METHODS FOR INDUCING CD8+ T-CELLS Russian patent published in 2021 - IPC C12N1/20 A61K35/74 A61K39/116 A61P35/00 

Abstract RU 2761873 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to the treatment of cancer. A pharmaceutical composition for the treatment of cancer is proposed, containing effective amount of a purified bacterial mixture consisting of bacterial strains containing 16S of rDNA sequence at least 99% identical to a sequence SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10 and SEQ ID NO: 11. A pharmaceutical composition for the treatment of cancer is also proposed, additionally containing a pH-sensitive composition containing one or several intestinal soluble polymers.

EFFECT: group of inventions activates the immune system by inducing interferon-gamma-producing CD8+ T-cells.

30 cl, 57 dwg, 4 tbl, 11 ex

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RU 2 761 873 C2

Authors

Khonda Kenya

Tanoue Takeshi

Khattori Masakhira

Kavakami Yutaka

Dates

2021-12-13Published

2017-12-22Filed