FIELD: medicine.
SUBSTANCE: peptide increasing the activity of guanylate cyclase C receptor and its use are proposed. Peptide increasing the activity of guanylate cyclase C receptor consists of a sequence of amino acids Cys1 Cys2 Glu3 Tyr4 Cys5 Cys6 Asn7 Pro8 Ala9 Cys10 Thr11 Gly12 Cys13 Tyr14, where disulfide bonds are present between Cys1-Cys6, Cys2-Cys10 and Cys5-Cys13. Peptide can be used in the composition of a pharmaceutical composition for an increase in intestinal motility in a patient or for the treatment of a patient with a gastrointestinal disorder. A method for producing the specified peptide and the use of the specified peptide for producing a drug for the treatment of a gastrointestinal disorder in a patient are also proposed.
EFFECT: invention provides for an increase in the activity of guanylate cyclase C receptor.
11 cl, 10 dwg, 2 tbl, 6 ex
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