FIELD: biochemistry.
SUBSTANCE: invention relates to the field of biochemistry, in particular to peptide containing less than 15 amino acids with the capability of inducing a cytotoxic T-cell (CTC) in the presence of antigen-presenting cell(s) expressing HLA-A*1101. Polynucleotide encoding the specified peptide; a composition, an emulsion, a kit containing the specified peptide; antigen-presenting cells containing the specified peptide are disclosed. Methods for the induction of an immune response, treatment or prevention using the specified peptide, a method for peptide screening; the use of a suitable dose of the specified peptide are also disclosed.
EFFECT: invention allows for the effective treatment of diseases associated with HLA-A*1101 factor.
21 cl, 9 dwg, 6 tbl, 3 ex
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Authors
Dates
2022-02-01—Published
2016-08-10—Filed