PEPTIDE DERIVED FROM FOXM1, AND INCLUDING ITS VACCINE Russian patent published in 2020 - IPC C07K7/04 C07K14/47 C12N5/783 C12N5/784 C12N15/12 A61K38/00 A61P35/00 

Abstract RU 2738418 C2

FIELD: immunology.

SUBSTANCE: disclosed are peptides derived from FOXM1 and capable of inducing a cytotoxic T-cell (CTL) in the presence of an antigen-presenting cell (APC) expressing HLA-A*01:01. Invention also describes: a coding polynucleotide; composition; methods for inducing APC and CTL; APC presenting HLA-A*01:01 and peptide; a method for inducing an immune response; method of treating and/or preventing a malignant tumor and/or preventing its postoperative recurrence; emulsion; set; as well as use of said inventions when preparing a pharmaceutical composition and a peptide screening method with ability to induce CTL.

EFFECT: this group of inventions can find application in therapy of diseases associated with FOXM1.

21 cl, 8 dwg, 2 tbl, 3 ex

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RU 2 738 418 C2

Authors

Yamashita, Sachiko

Hikichi, Tetsuro

Dates

2020-12-14Published

2016-10-06Filed