FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular to an artificial antigen-presenting cell (aAPC), as well as to the method for its preparation. Also disclosed is the use of the above cell in a method for activating an antigen-specific T-cell, a method for inducing T-cell proliferation, a method for expanding a subpopulation from a T-cell population, as well as in a method for inducing a T-cell response to the HPV-E7 antigen.
EFFECT: invention is effective for the treatment of an individual with HPV-positive malignant neoplasm.
34 cl, 17 dwg, 29 tbl, 27 ex
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