SYNP198, PROMOTOR FOR SPECIFIC GENE EXPRESSION IN RETINAL GANGLION CELLS SELECTIVE RELATIVELY TO DIRECTION Russian patent published in 2022 - IPC A61K48/00 C12N15/85 

Abstract RU 2766353 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to the field of biotechnology, in particular to an isolated molecule of a nucleic acid-promotor. The invention can be used as an endogenous regulatory element, and it allows for specific expression of a gene of interest in retinal ganglion cells selective relatively to the direction, provided that there is a functional connection of the promotor to a nucleic acid sequence encoding the specified gene.

EFFECT: invention can be used for the development of systems for the research of neurodegenerative disorders, vision restoration and diagnostics of various eye disorders.

13 cl, 1 ex, 1 dwg

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RU 2 766 353 C2

Authors

Hartl, Dominik

Juettner, Josephine

Krebs, Arnaud

Roska, Botond

Schuebeler, Dirk

Dates

2022-03-15Published

2017-11-01Filed