SYNP161, PROMOTER FOR SPECIFIC GENE EXPRESSION IN ROD PHOTORECEPTORS Russian patent published in 2021 - IPC A61K48/00 C12Q1/68 C12N15/63 C12N15/86 

Abstract RU 2758211 C2

FIELD: medicine.

SUBSTANCE: expressing cassette is proposed containing an isolated nucleic acid molecule containing or consisting of a nucleic acid sequence SEQ ID NO: 1 functionally connected to at least a nucleic acid sequence encoding a gene, where the specified isolated nucleic acid molecule is effective for directing the gene expression in a rod photoreceptor cell. A vector containing the specified expressing cassette is proposed. A method for expressing a gene in a rod photoreceptor cell and use of the expressing cassette for expressing a gene in a rod photoreceptor cell are proposed.

EFFECT: proposed group of inventions provides for the control of expressing operatively bound gene in a rod photoreceptor cell through a functionally connected isolated nucleic acid molecule.

8 cl, 1 dwg, 1 ex

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RU 2 758 211 C2

Authors

Hartl, Dominik

Schuebeler, Dirk

Roska, Botond

Krebs, Arnaud

Juettner, Josephine

Dates

2021-10-26Published

2016-12-01Filed