RECOMBINANT PROTEINS AND THEIR APPLICATIONS IN THERAPEUTIC PURPOSES Russian patent published in 2022 - IPC C07K14/28 C07K14/485 C07K14/475 C07K14/495 C07K14/50 C07K14/65 C07K14/71 A61K39/00 

Abstract RU 2766595 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to the field of biotechnology, specifically to recombinant protein for producing neutralizing antibodies against one or several growth factors. An artificially constructed protein molecule, according to the present invention, includes several fragments interconnected by a short peptide linker, selected from immunogen peptide and neutralizing domain of one or more human growth factors, which are mediators of cell proliferation in different cancer types.

EFFECT: invention can be used in the production of vaccines for immunotherapy of tumor diseases.

15 cl, 44 dwg, 14 ex

Similar patents RU2766595C2

Title Year Author Number
RECOMBINANT PROTEINS AND THEIR THERAPEUTIC USES 2012
  • Charlton Kit Alan
  • D'Ondt Erik
RU2650574C2
SELF-ASSEMBLY SYNTHETIC PROTEINS 2014
  • Charlton, Keith, Alan
  • D'Hondt, Erik
  • Verhamme, Daniel, T.
RU2801230C2
SELF-ASSEMBLING SYNTHETIC PROTEINS 2014
  • Charlton, Keith, Alan
  • D'Hondt, Erik
  • Verhamme, Daniel, T
RU2747857C2
THERAPEUTIC COMPOSITION FOR REDUCING RESISTANCE TO TYROSINE KINASE INHIBITORS 2016
  • D'Hondt, Erik
  • Molina Vila, Miguel, Angel
RU2735493C2
COMBINATIONS OF GROWTH-REGULATING FACTORS AND HORMONES FOR NEOPLASIA TREATMENT 2003
  • Bover Fuentes Ehddi
  • Basul'To Baker Roberto
  • Pimentel' Vaskes Ehulokhio
  • Khunko Barranko Khesus
  • Fuentes Agilar Franklin
  • Artega More Niurka
  • Kal'Sada Agilera Lesvija
  • Ehrnandes Dominges Ehktor
  • Lopes Saehs Evislejdis
  • Gill'En N'Eto Kherardo Ehnrike
  • Chinea Sant'Jago Glaj
RU2321422C2
HUMAN ANTIBODIES TO RECEPTOR OF EPIDERMAL GROWTH FACTOR 2005
  • Li Mellin
  • Zhu Zhenpin
RU2402569C2
RECEPTOR ANTAGONISTS FOR TREATING METASTATIC CANCER 2009
  • Loizos Nik
  • Kh'Juber Dzhim
RU2455026C2
BISPECIFIC BINDING AGENTS FOR MODULATING BIOLOGICAL ACTIVITY 2005
  • Nilsen Ulrik B.
  • Shoehberl' Birgit M.
RU2433831C2
PDGFRα ANTIBODIES FOR TREATING SECONDARY BONE TUMOUR 2006
  • Ljudvig Dejl L.
  • Plajmejt Stefen R.
  • Loizos Nik
  • Kh'Juber Dzhim
  • Fatatis Alessandro
RU2502523C2
MEANS OF IDENTIFICATION OF TUMOURS, ACQUISITIVE TO TREATMENT BY ANTIBODIES AGAINST ErbB2 2003
  • Koll' Khans
  • Bossenmajer Birgit
  • Mjuller Khans-Joakhim
  • Slivkovski Mark K.
  • Kelsi Stefen Majkl
RU2338751C2

RU 2 766 595 C2

Authors

Charlton, Kit, Alan

D'Ondt, Erik

Dates

2022-03-15Published

2018-03-09Filed