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2 767 398

(13)

(51)

IPC

C07D471/04(2006-01-01)

C07D257/02(2006-01-01)

A61K31/555(2006-01-01)

A61K49/00(2006-01-01)

A61K51/04(2006-01-01)

A61K103/20(2006-01-01)

A61K103/32(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2020115068, 2016-03-25

(24)

Start date

2016-03-25

(22)

Actual filing date

2016-03-25

(45)

Published

2022-03-17

(72)

Inventor

Fukunaga, HirofumiShinjo, SachikoNakagawa, DaisukeSekine, ShinichiroYamakawa, Takayuki

(73)

Holder

Fujifilm Corporation

USE OF COMPLEX OF NITROGEN-CONTAINING COMPOUND WITH METAL FOR DIAGNOSTICS OR TREATMENT OF TUMORS WITH INTEGRIN EXPRESSION Russian patent published in 2022 - IPC C07D471/04 C07D257/02 A61K31/555 A61K49/00 A61K51/04 A61K103/20 A61K103/32 A61P35/00

Abstract RU 2767398 C2

FIELD: medicine.

SUBSTANCE: invention relates to the use of a complex of a compound with metal for the treatment of tumors with integrin expression, wherein the specified compound is 2,2', 2''-(10-(2-(((R)-1-((2-(4-(4-(N-((S)-1-carboxy-2-(5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanamide)ethyl)sulfamoyl)-3,5-dimethylmethoxy)butanamide)ethyl)amino)-1-oxo-3-sulfopropan-2-yl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid and the specified metal is Lu.

EFFECT: providing the treatment of tumors with integrin expression.

2 cl, 6 dwg, 7 tbl, 17 ex

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RU 2 767 398 C2

Authors

Fukunaga, Hirofumi

Shinjo, Sachiko

Nakagawa, Daisuke

Sekine, Shinichiro

Yamakawa, Takayuki

Dates

2022-03-17—Published

2016-03-25—Filed