TCh (TESTIS CAPRA hircus), TRANSPLANTABLE MONOLAYER SUBLINE OF TESTICLE CELLS OF A MONTH-OLD GOATLING INTENDED FOR REPRODUCTION OF SMALLPOX VIRUSES, PLAGUE OF SMALL RUMINANTS AND INFECTIOUS BOVINE NODULAR DERMATITIS, AS WELL AS FOR MAKING DIAGNOSTIC AND PREVENTIVE VETERINARY BIOPREPARATIONS Russian patent published in 2022 - IPC C12N5/76 

Abstract RU 2768962 C1

FIELD: biotechnology.

SUBSTANCE: present invention relates to the field of biotechnology, cytology and virology, in particular to the testis cell line Testis Capra hircus (TCh), intended for reproduction of viruses when producing viral material, used for making diagnostic and preventive veterinary biopreparations. Presented TCh cell line is obtained from a monolayer transplantable subline YDC-04 as a result of prolonged passage in a growth medium of the original composition PSP + 199 with addition of 10 % lanthanide-treated bovine blood serum. TCh culture is deposited in the Specialized collection of cell cultures of the Centre for Collective Use Collection of Vertebrate Cell Cultures of the Institute of Cytology of the Russian Academy of Sciences under number RKKK(P) 796 D.

EFFECT: invention enables to obtain a culture of goat cells with increased and more stable rate of sieving and reliable reproduction of viruses of smallpox of ruminants, plague of small ruminants and infectious nodular dermatitis of cattle.

6 cl, 15 dwg, 6 tbl, 7 ex

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RU 2 768 962 C1

Authors

Manin Boris Leonidovich

Trofimova Elena Aleksandrovna

Gusarova Svetlana Evgenevna

Kononova Svetlana Vladimirovna

Shumilova Irina Nikolaevna

Vologina Irina Viktorovna

Kolchanov Nikolaj Aleksandrovich

Dates

2022-03-25Published

2021-04-12Filed