COMPOSITION FOR TREATING FIBROTIC DISEASES CONTAINING BENZHYDRYLTHIOACETAMIDE AS ACTIVE INGREDIENT Russian patent published in 2022 - IPC A61K31/165 A61K31/167 A61K31/341 A61P1/16 A61P43/00 

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention relates to use of a pharmaceutical composition containing an effective amount of a compound of formula A or a pharmaceutically acceptable salt thereof as an active ingredient and having the effect of inhibiting the expression of the K_Ca2.3 channel protein in the cell membrane for the treatment of hepatic fibrosis or pulmonary fibrosis. In formula A, each of X₁ ~ X₁₀ independently represents hydrogen (H) or fluorine (F), all of which may be the same or different from each other; Y is sulfur (S) or sulfoxide (S=O), * indicates a chiral position; R₁ is any of hydrogen, a methyl group, a hydroxyl group, a phenyl group and (tetrahydrofuran-2-yl) methyl.

Formula A.

EFFECT: treating hepatic fibrosis and pulmonary fibrosis by using a pharmaceutical composition containing an effective amount of a compound of formula A or a pharmaceutically acceptable salt thereof, which inhibits expression of K_Ca2,3 channel protein in the cell membrane.

6 cl, 13 dwg, 4 tbl, 2 ex