NEW DERIVATIVES OF PICOLINIC ACID AND THEIR USE AS INTERMEDIATE COMPOUNDS Russian patent published in 2022 - IPC C07D213/79 C07D213/81 A61P11/00 A61K31/435

Abstract RU 2769693 C2

FIELD: pharmaceutics.

SUBSTANCE: invention relates to new derivatives of picolinic acid of the formula (I) and their use as intermediate compounds in a method for producing pyridine derivatives, including (S)-3-amino-6-methoxy-N-(3,3,3-trifluoro-2-hydroxy-2-methylpropyl)-5-(trifluoromethyl)picolinamide.

EFFECT: new derivatives of picolinic acid of the formula (I) are obtained that can be used as intermediate compounds in a method for producing pyridine derivatives that are suitable for the treatment of respiratory disorders.

20 cl, 5 ex

Similar patents RU2769693C2

Title	Year	Author	Number
MACROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE	2019	Azimioara, Mihai Bursulaya, Badry Jiang, Songchun Mathison, Casey Jacob Nelson Nikulin, Victor Ivanovich Nguyen, Truc Ngoc Okram, Barun Patel, Sejal Phillips, Dean Paul Whitehead, Lewis Wu, Baogen Yan, Shanshan Zhu, Xuefeng	RU2804139C2
N-(2-CYANO HETEROCYCLYL)PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS	2014	Dinsmor, Kristofer Fuller, Piter Gerin, Devid Tompson, Kristofer F. Pu, Tsinlin Skott, Mark E. Katts, Dzhejson Devid Kurukulasuriya, Ravi Klouz, Dzhoshua T. Folkon, Deniell Brubejker, Dzhejson Tszen, Khunbo Baj, Yunfyn Fu, Tszyanmin Kun, Norman Lyu, Yujmej Chzhen, Chzhisyan	RU2669922C2
N-(2-BENZYL)-2-PHENYLBUTANAMIDES AS ANDROGEN RECEPTOR MODULATORS	2005	Khanni Barbara Kim Juntae Krout Majkl R. Mejssner Robert S. Mitchell Khelen Dzh. Masselman Dzheffri Perkins Dzhejms Dzh. Vang Dziabing	RU2378255C2
PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA	2013	Achab Abdelgkhani Abe Altman Majkl D. Deng Jongki Kattar Solomon Katts Dzhejson D. Metot Dzhon L. Chzhou Khua Makgovan Meredet Kristofer Mettyu P. Garsiya Yudit Entoni Nevill Dzhon Fradera Linas Fransesk Ksaver Yan Lipin Mu Chanvej Van Syaona Shi Fen E Bajtszyun Chzhan Sisin Chzhao Syaoli Chzhan Zhun Fong Kin Chiu Len Syanshen	RU2661896C2
TRANSGLUTAMINASE 2 (TG2) INHIBITORS	2019	Campbell, David Chapman, Justin Cheung, Mui, H. Diraimondo, Thomas, R. Duron, Sergio, G.	RU2781370C2
NEW COMPOUND OF BENZIMIDAZOLONE AND ITS PHARMACEUTICAL USE	2018	Mizushima, Shingo Watanabe, Masaki Iwamoto, Kohei Urashima, Kuniko	RU2803938C2
AMIDES OF CONDENSED PIPERIDINE AS MODULATORS OF ION CHANNELS	2014	Deninno Majkl Pol Anderson Kori Konroj Erika Linn Friman Brajan A. Grotenkhejs Peter Diderik Yan Adida-Rua Sara Sabina Kharli Dennis Dzhejms Per Fabris Zhan Denis Silina Alina Yu Dzhonni Chzhou Tszinlan	RU2741810C2
PESTICIDE COMPOSITIONS AND RELATED METHODS	2012	Khanter Dzhejms E. Lo Ulyam S. Uotson Dzherald B. Patni Akshaj Gustavson Gari D. Pernich Den Bryuster Uilyam K. Kamper Debra L. Lorsbakh Bet Loso Majkl R. Sparks Tomas S. Dzhoshi Khemant Mandalesvaran Adiraj Sanam Ramadevi Gundla Rambabu Ajer Pravin S.	RU2614976C2
AMIDE DERIVATIVES AS GRP119 AGONISTS	2014	Kim Yuntkhe Li Chansik Tsoj Teke Ko Muson Khan Yunkhue Kim Soyun Min Cheki Kim Tokhun	RU2642429C2
SPIROCYCLIC PYRROLOPYRAZINE(PIPERIDINE)AMIDES AS IONIC CHANNELS MODULATORS	2012	Adida Rua Sara S. Kallel Edvard Adam Miller Mark Tomas Arumugam Vidzhayalaksmi Makkartni Dzhejson Anderson Kori Grotenkhejs Peter Diderik Yan Dzhiang Likong	RU2634900C2

RU 2 769 693 C2

Authors

Khajnts, Tomas

Martin, Benyamin

Rampf, Florian Andreas

Tsaugg, Verner

Dates

2022-04-05—Published

2017-12-18—Filed