FIELD: medicine; pharmaceutics.
SUBSTANCE: invention relates to a heterocyclic compound of the formula (I), its isomer or pharmaceutically acceptable salt, R1 is selected from hydrogen and fluorine; R2 is selected from fluorine and C1-2alkoxy; R3 is selected from hydrogen and methoxy, and R4 is C1-3alkyl optionally substituted with a group selected from C1-3alkoxy and NR5R6, where each of R5 and R6 is independently methyl; or 4-6-element heterocyclic ring containing one oxygen atom. The invention also relates to a pharmaceutical composition based on the compound of the formula (I), its isomer or pharmaceutically acceptable salt, their use and a method for the treatment of KIT-mediated cancer.
EFFECT: new compounds are obtained, suitable for the treatment of KIT-mediated cancer.
20 cl, 10 dwg, 5 tbl, 22 ex
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