BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS Russian patent published in 2022 - IPC C07D401/12 C07D417/12 C07D451/02 A61K31/4427 A61P25/08 

Abstract RU 2769827 C2

FIELD: organic chemistry.

SUBSTANCE: invention relates to (S)-4-((1-benzylpyrrolidin-3-yl)(methyl)amino)-2-fluoro-5-methyl-N-(thiazol-4-yl)benzenesulfonamide or a pharmaceutically acceptable salt or solvate thereof. Invention also relates to a pharmaceutical composition based on said compound and use thereof.

EFFECT: obtaining a heterocyclic compound which is useful in treating a disease or condition associated with NaV1,6 activity, where the disease or condition is epilepsy and/or epileptic seizures.

12 cl, 1 tbl, 331 ex

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RU 2 769 827 C2

Authors

Andre, Zhan-Kristof

Berford, Kristen, Nikol

Chovdkhuri, Sultan

Koen, Charlz, Dzhej

Denkhardt, Kristof, Martin

Devita, Robert, Dzhozef

Empfild, Dzhejms, Roj

Fokken, Tilo

Grimvud, Majkl, Edvard

Khasan, Sajed, Abid

Dzhonson, Dzhejms, Filip, Ml.

Zenova, Alla, Yurevna

Dates

2022-04-06Published

2017-05-19Filed