FIELD: pharmaceutical compositions.
SUBSTANCE: present invention relates to the use of a pharmaceutical composition for buccal/gingival administration of paracetamol, consisting of a water-alcohol solution containing dissolved paracetamol, where the mass of paracetamol is from 95 mg to 190 mg, the volume of the specified aqueous-alcoholic solution is from 1.0 ml to 2 0 ml, the alcohol content (in degrees) in said water-alcohol solution is from 48.5 to 52.5%, and the concentration of paracetamol in said water-alcohol solution is from 85 mg/ml to 110 mg/ml, to increase the rate at which paracetamol passes through the blood-brain barrier.
EFFECT: creation of pharmaceutical composition for buccal/gingival administration of paracetamol.
6 cl, 7 dwg, 3 tbl
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Authors
Dates
2022-04-26—Published
2018-02-28—Filed