NEW COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING, AND SYNTHESIS, NANO-STRUCTURE AND USE THEREOF Russian patent published in 2018 - IPC C07K5/37 C07K5/97 C07D217/26 A61K47/55 A61K38/06 A61P7/02 A61P39/06 

Abstract RU 2660901 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of formula I wherein AA is selected from the group consisting of L-Ala, L-Val, L-Trp, L-Tyr, L-Pro, L-Phe, Gly, L-Ser, L-Ile, L-Thr, L-Lys, L-Leu, L-Gln, L-Asn, L-Asp and L-Glu, simultaneously possessing triple activity in the form of thrombolysis, antithrombosis and free radical scavenging, as well as to the method for preparing the composition.

.

EFFECT: compounds are intended for the treatment of stroke or cerebral infarction.

7 cl, 9 dwg, 13 tbl, 68 ex

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RU 2 660 901 C2

Authors

Pen Shiki

Zhao Min

Vu Tszyankhuej

Van Yujtszi

Fen Tsitsi

Dates

2018-07-11Published

2014-06-03Filed