CELLULAR SYSTEM FOR TARGETED DELIVERY OF A PHARMACEUTICALLY ACTIVE SUBSTANCE OR LABEL Russian patent published in 2022 - IPC C12N5/786 C12N5/781 C12N5/783 C12N5/787 A61K35/15 A61K35/17 A61K38/42 

Abstract RU 2771323 C2

FIELD: medicine.

SUBSTANCE: invention relates to the field of cellular biology and medicine, in particular, to a system for directed delivery and to a method for producing such a system. Said system comprises a cell constituting a CD45+ leukocyte, selected, in particular, from a CD45+ monocyte, a CD45+ monocyte macrophage, a CD45+ lymphocyte, or a CD45+ granulocyte. Said cell therein contains a complex of at least one iron-binding protein and a pharmaceutically active substance and/or label.

EFFECT: invention ensures delivery of pharmaceutically active substances and/or labels to cells in poorly or non-vascularised areas; reduction in the side effects of medicinal products due to the targeted delivery thereof; and higher effectiveness of treatment by lower doses of medicinal products due to the targeted delivery thereof.

41 cl, 27 dwg, 18 ex

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RU 2 771 323 C2

Authors

Krul, Magdalena

Benni, Iren

Bajokko, Paola

Rygel, Tomash

Boffi, Alberto

Shults, Aleksandra

Plikh, Sofiya

Tonetskaya, Katazhina

Ulevich, Katazhina

Tatsyak, Bartolomej

Kiraga, Lukash

Dates

2022-04-29Published

2016-12-21Filed