ANTIBODIES BINDING TO PD-1 AND THEIR APPLICATIONS Russian patent published in 2022 - IPC A61K39/395 C07K16/28 C07K14/705 

Abstract RU 2773758 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to the field of biotechnology, in particular to a new antibody, and can be used in medicine.

EFFECT: invention makes it possible to obtain an isolated monoclonal antibody capable of binding to PD-1 with increased affinity, and discloses the possibility of its use, including as part of a pharmaceutical composition, to suppress the growth of tumor cells in the treatment of various cancers.

11 cl, 12 tbl, 2 dwg, 10 ex

Similar patents RU2773758C2

Title Year Author Number
HIGH-AFFINITY ANTI-PD-1 AND ANTI-LAG-3 ANTIBODIES AND BISPECIFIC BINDING PROTEINS OBTAINED FROM THEM 2019
  • Wu, Xuan
  • Gong, Shiyong
  • Wu, Chengbin
RU2782381C2
IMMUNOCYTOKINES AND THEIR USE 2021
  • Wu Ellen
  • Wu Xiaoyun
  • Wakefield John
RU2818371C1
ANTIBODIES TO PD-1 AND THEIR APPLICATION 2017
  • Mabry, George Robert, Iii
  • Sazinsky, Stephen
RU2761640C2
ANTI-PD-L1 AND IL-2 CYTOKINES 2017
  • Kempbell Dzhejmi
  • Sendi Nikol
  • Van Krinks Kassandra
  • Arkinstoll Stiven Dzhon
  • Germashevski Volker
  • Kerbi Ien
  • Kosmak Mikha
  • Gellager Tomas
  • Dintonio Sesiliya
  • Dzhillis Stiven Duglas
RU2769282C2
PD-L1 SPECIFIC ANTIBODIES 2017
  • Campbell Jamie
  • Sandy Nikole
  • Van Krinks Cassandra
  • Arkinstall Stephen John
  • Germaschewski Volker
  • Kirby Ian
  • Kosmac Miha
  • Gallagher Thomas
  • Deantonio Cecilia
  • Gillies Stephen Douglas
RU2756236C2
NEW ANTIBODY COMPOSITIONS FOR CANCER IMMUNOTHERAPY 2019
  • Li, Chian Dzh.
  • Unniraman, Shiam
  • Bader, Khanna
  • Dzhkha, Mitilesh
RU2804490C2
ANTIBODIES AGAINST SIGNAL-REGULATORY ALPHA PROTEIN AND THEIR APPLICATION METHODS 2017
  • Pons, Jaume
  • Sim, Bang Janet
  • Wan, Hong
  • Kuo, Tracy Chia-Chien
  • Kauder, Steven Elliot
  • Harriman, William Don
  • Izquierdo, Shelley
RU2771964C2
IMMUNOGLOBULIN WITH TANDEM FAB- FRAGMENTS AND ITS APPLICATION OPTIONS 2017
  • U, Chenbin
RU2767329C2
BISPECIFIC ANTIBODY 2020
  • Shibayama, Shiro
  • Tezuka, Tomoya
  • Throsby, Mark
  • De Kruif, Cornelis Adriaan
  • Van Loo, Pieter Fokko
  • Klooster, Rinse
  • Roovers, Robertus Cornelis
RU2814713C2
BISPECIFIC ANTIGEN-BINDING MOLECULES CONTAINING ANTI-FAP CLONE 212 2019
  • Bruenker Peter
  • Duerr Harald
  • Klein Christian
  • Umana Pablo
  • Bujotzek Alexander
  • Zielonka Joerg
  • Trumpfheller Christine
  • Rapp Moritz
  • Le Clech Marine
RU2799429C2

RU 2 773 758 C2

Authors

Chen, Mintszyu

Tan, Vej

Dates

2022-06-09Published

2019-04-12Filed