FIELD: medicine.
SUBSTANCE: group of inventions relates to the field of medicine, namely, to implantable stents containing a drug coating and to a method for production thereof. Stent includes a polymer selected for a biostable or biodegradable drug coating and constituting a polylactide or a fluoropolymer, and a therapeutic agent retaining the therapeutic activity in combination with the selected polymer formed by coating the stent surface with an aerosol formed from a liquid composition with a kinematic viscosity of 0.5 cSt to 1.5 cSt, followed by drying the aerosol applied to the stent surface. The claimed stent is produced by an original method.
EFFECT: group of inventions allows for delivery of a therapeutic agent to the treatment site and control over the rate of release thereof with the maintained integrity and performance during all manipulations performed with the stent prior to implantation in the vessel.
21 cl, 5 dwg, 2 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| STENT WITH DOUBLE DRUG RELEASE | 2010 |
|
RU2552086C2 |
| RAPAMICIN-RELEASING STENT | 2010 |
|
RU2563429C2 |
| BARE METAL STENT WITH MEDICATION-RELEASING RESERVOIRS | 2011 |
|
RU2573107C2 |
| METHOD OF PRODUCING BIODEGRADABLE POLYMER COATING BASED ON POLYLACTIDE ON TiNbTaZr WIRE | 2018 |
|
RU2686747C1 |
| THIN STRUT STENT FROM BIOABSORBABLE POLYMER WITH HIGH FATIGUE AND RADIAL STRENGTH AND METHOD FOR MANUFACTURE THEREOF | 2014 |
|
RU2667649C2 |
| METHODS AND COMPOSITIONS CONTAINING CLONIDINE, APPLICABLE FOR TREATING POSTOPERATIVE PAIN | 2009 |
|
RU2510263C2 |
| ADHESION-STIMULATING TEMPORARY MASK FOR COATED SURFACES | 2009 |
|
RU2526885C2 |
| COMPOUNDS CONTAINING CLONIDINE IN DEGRADABLE POLYMER | 2009 |
|
RU2494731C2 |
| STENT | 2007 |
|
RU2432183C9 |
| DEVICE FOR LOCAL AND/OR REGIONAL DELIVERY USING LIQUID FORMULATIONS OF THERAPEUTICALLY ACTIVE SUBSTANCES | 2009 |
|
RU2596092C2 |
