FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical industry and represents an implanted depot of a therapeutic agent for relieving, preventing or treating pain in a patient in need thereof, containing clonidine in the amount of 1 wt % to 15 wt % of the depot of the therapeutic agent, and at least one biodegradable polymer; the above depot of the therapeutic agent has a surface that provides releasing a peak dose of clonidine in the amount of 5 wt % to 20 wt % of total amount of clonidine in the above depot for 24 hours and releasing the effective amount of clonidine for a period of at least three days; the above polymer has characteristic viscosity 0.45 dl/g to 0.55 dl/g and contains poly(D,L-lactide), while said clonidine contains clonidine hydrochloride.
EFFECT: invention extends the range of products for relieving pain.
9 cl, 2 ex, 5 tbl, 34 dwg
