METHOD FOR TREATMENT OF POLYCYSTIC OVARIAN SYNDROME BASED ON EXPERIMENTAL MODEL OF WISTAR RATS Russian patent published in 2022 - IPC G09B23/28 A61K31/05 A61P5/26 A61P15/00 

Abstract RU 2776131 C1

FIELD: experimental medicine.

SUBSTANCE: invention relates to experimental medicine, namely to obstetrics and gynecology, and can be used for the treatment of polycystic ovary syndrome (PCOS) in an experimental model of Wistar rats. The method consists in the fact that on the model of drug-induced polycystic ovary syndrome using letrozole at a dosage of 800 mcg/day or 400 mcg /day for 60 days, oral administration of natural phytoalexin resveratrol is performed at a dosage of 30 mg/kg/day or 20 mg/day. kg/day for 30 days.

EFFECT: invention helps to restore the estrous cycle, reduce body weight, reduce cystic changes, increase the layer of granular cells, as well as the appearance of oocytes.

1 cl, 1 ex, 3 dwg

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RU 2 776 131 C1

Authors

Yarmolinskaya Mariya Igorevna

Bulgakova Olga Leonidovna

Abashova Elena Ivanovna

Borodina Valentina Leonidovna

Tral Tatyana Georgievna

Dates

2022-07-13Published

2021-09-22Filed