FIELD: medicine.
SUBSTANCE: present invention is referred to experimental medicine and can be used for creation of model of polycystic ovaries. For this purpose use preadolescent females of rats of line Vistar at the age of 30 days, with mass of 30-35 grams and absence of regular estrous 4-day cycles. The Estrogele preparation in a dose of 2.5 grams unitary apply with a plastic batcher on skin of an abdominal wall of a rat preliminary cleared from coat. Then fix an animal for 10-15 minutes to a full absorption of the preparation. Further immobilise the animal daily for 15 minutes within 1 month.
EFFECT: creation of model for more detailed studying of mechanisms of formation of a polycystic ovaries syndrome.
1 ex, 3 dwg
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