FIELD: chemistry.
SUBSTANCE: group of inventions relates to a method for the production of microparticles for incapsulating active substance, including (a) obtaining the first phase containing active substance; (b) obtaining the second phase containing a carrier and a solvent; (c) passing the first phase and the second phase through membrane to form a primary emulsion; (d) passing the primary emulsion through a micro-sieve to a dispersion phase to form a secondary emulsion, and (e) removing the solvent to form microparticles, as well as to microparticles for incapsulating active substance, obtained using the method.
EFFECT: group of inventions provides the development of a method for the production of microparticles with the same size and narrow particle distribution by size.
15 cl, 6 dwg, 2 tbl, 5 ex
| Title |
Year |
Author |
Number |
| NEW METHODS |
2014 |
- Vanover Kimberli
- Li Pen
- Mejts Sheron
- Devis Robert
- Uennogl Lourens P.
|
RU2682658C1 |
| PREPARATION OF POLYLACTIDE-POLYGLYCOLIDE MICROPARTICLES CHARACTERISED BY SIGMOIDAL RELEASE PROFILE |
2014 |
- Karavas, Evangelos
- Koutris, Efthymios
- Haitidou, Sotiria
- Mantourlias, Theofanis
- Papanikolaou, Georgia
|
RU2658004C2 |
| STABILIZED CHEMICAL COMPOSITION |
2019 |
- Fowler Jeffery David
- Kim Sejong
- Lebedeva Natalia
- Narsale Jelena
|
RU2820174C2 |
| INJECTABLE COMPOSITION WITH SUSPENDED RELEASE CONTAINING A CONJUGATE OF A FILLER WITH POLY-L-LACTIC ACID, A FILLER WITH HYALURONIC ACID AND A BIOACTIVE MATERIAL, AND A METHOD FOR ITS PREPARATION |
2020 |
|
RU2777623C1 |
| IMPROVED RELEASE PROFILE MICROPARTICLES AND METHOD FOR PRODUCING THE PARTICLES |
2001 |
- Kissel Tomas
- Fridrikh Ruland
- Shnajder Peter
|
RU2291686C2 |
| DELAYED-RELEASE INJECTION COMPOSITION CONTAINING A CONJUGATE OF A FILLER WITH POLY-L-LACTIC ACID AND A FILLER WITH HYALURONIC ACID, AND METHOD FOR PRODUCTION THEREOF |
2020 |
|
RU2777621C1 |
| STABILIZED CHEMICAL COMPOSITION |
2019 |
- Fowler Jeffery David
- Kim Sejong
- Lebedeva Natalia
- Narsale Jelena
|
RU2801250C2 |
| EMULSION FOR MICROENCAPSULATION CONTAINING BIODEGRADABLE SURFACTANT BLOCK COPOLYMERS AS STABILIZERS |
2011 |
|
RU2617057C2 |
| METHOD FOR OBTAINING NATIVE PROTEIN WITH PROLONGED ACTION IN THE COMPOSITION OF POLYMERIC NANOSPHERES AND RESORBED MICROSPHERES FOR DELIVERY |
2016 |
- Nozdrachev Aleksandr Danilovich
- Goryukhina Olga Aleksandrovna
- Martyushin Sergej Vasilevich
- Mishchenko Ilya Vladimirovich
|
RU2647466C1 |
| METHOD FOR MANUFACTURE OF MICROSPHERES CONTAINING MEDICINAL SUBSTANCES AS BIOLOGICALLY ACTIVE SUBSTANCE, ENCLOSED IN POLYMER MATRIX, USING MICROSPHERES PRODUCTION BY DOUBLE EMULSION METHOD |
2016 |
- Nazarenko Anna Borisovna
- Kinasov Dmitrij Gurgenovich
- Ladygin Vyacheslav Vladimirovich
- Zakoryukin Nikolaj Valentinovich
- Kornev Kirill Olegovich
|
RU2635472C1 |
