IMPROVED PHARMACEUTICAL COMPOSITIONS Russian patent published in 2022 - IPC A61K9/14 A61K47/06 A61K47/10 A61K31/4545 A61K31/4725 A61K31/519 

FIELD: pharmaceutics.

SUBSTANCE: free-flowing pharmaceutical composition is proposed, containing (1) lyophilized granules containing one or several active ingredients, and (2) a composition of a mixture, containing sorbitol and vaseline oil, where the composition contains from 0.01% to 30% by weight of the active ingredient(s), from 70% to 99.99% by weight of the composition of a mixture, and from 0% to 29.99% by weight of other pharmaceutically acceptable excipients. At the same time, the composition of a mixture contains from 955 to 99.9% by weight of sorbitol, from 0.1% to 5% by weight of vaseline oil, and from 0% to 4% by weight of citric acid. A packaging containing the specified pharmaceutical composition, a method for the manufacture of the specified composition, and the use of a solid mixture containing sorbitol and vaseline oil in the specified amount for the manufacture of a pharmaceutical composition are also proposed.

EFFECT: obtained composition has improved properties of fluidity, moisture protection, antistatic properties, as well as high uniformity of anti-adhesive properties preventing adhesion.

16 cl, 17 dwg, 9 ex