MR-proADM AS MARKER FOR EXTRACELLULAR VOLUME STATUS OF SUBJECT Russian patent published in 2022 - IPC G01N33/74 A61B5/00 

FIELD: medicine.

SUBSTANCE: method includes determination in a subject’s sample of a level of a marker of proadrenomedullin (hereinafter – proADM) or its fragment, preferably MR-proADM. Depending on the level of proADM or its fragment, a status of an extracellular liquid volume, a status of a liquid-salt balance, and a status of a subject’s globular volume are determined. The invention also relates to the use of a kit for the implementation of the specified methods. In addition, the invention relates to in vitro prediction of aggravation of symptoms in a subject.

EFFECT: group of inventions provides for the accuracy of detection of a status of an extracellular liquid volume, a status of a liquid-salt balance, and a status of a subject’s globular volume.

18 cl, 7 dwg, 16 tbl, 4 ex