USE OF CXCR4 ANTAGONISTS Russian patent published in 2022 - IPC A61K31/395 A61P31/00 A61P37/00 

Abstract RU 2780320 C2

FIELD: pharmaceutics.

SUBSTANCE: invention relates to the treatment of WHIM syndrome. A method for the treatment or prevention of WHIM syndrome in a human, who needs it, includes the injection to the specified human of CXCR4 antagonist in the amount effective for the treatment or prevention of WHIM syndrome. According to the invention, CXCR4 antagonist is N-[4-(11-sulfoxo-1,4,7-triazacyclotetradecanil)-1,4-phenylenbis(methylene)]-2-(aminomethyl)pyridine

or its pharmaceutically acceptable salt or metal complex.

EFFECT: invention provides for expanding the arsenal of means of a specific purpose.

9 cl, 2 dwg, 1 ex

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RU 2 780 320 C2

Authors

Dale, David, C.

Bridger, Gary, J.

Hsu, Frank, J.

Dates

2022-09-21Published

2012-05-15Filed